Psilocybin Research
Psilocybin is being studied for possible therapeutic applications, including treatment-resistant depression and end-of-life psychological distress. Findings remain investigational, and psilocybin is not currently approved for general clinical use.
Selected Research
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
JAMA Psychiatry · 2021
A randomized clinical trial examining psilocybin-assisted therapy in adults with major depressive disorder within a carefully structured research setting.
View Original Source → - Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression
The New England Journal of Medicine · 2022
A phase 2 trial comparing psilocybin doses in adults with treatment-resistant depression, including findings related to symptom change and adverse events.
View Original Source → - Single-Dose Psilocybin Treatment for Major Depressive Disorder
JAMA · 2023
A randomized clinical trial evaluating a single psilocybin dose administered with psychological support for major depressive disorder.
View Original Source →